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BMP type II receptors have redundant roles in the regulation of hepatic hepcidin gene expression and iron metabolism
Expression of hepcidin, the hepatic hormone controlling iron homeostasis, is regulated by bone morphogenetic protein (BMP) signaling. We sought to identify which BMP type II receptor expressed in hepatocytes, ActR2a or BMPR2, is responsible for regulating hepcidin gene expression. We studied Bmpr2 h...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4186540/ https://ncbi.nlm.nih.gov/pubmed/25075125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-572644 |
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