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BMP type II receptors have redundant roles in the regulation of hepatic hepcidin gene expression and iron metabolism
Expression of hepcidin, the hepatic hormone controlling iron homeostasis, is regulated by bone morphogenetic protein (BMP) signaling. We sought to identify which BMP type II receptor expressed in hepatocytes, ActR2a or BMPR2, is responsible for regulating hepcidin gene expression. We studied Bmpr2 h...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4186540/ https://ncbi.nlm.nih.gov/pubmed/25075125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-572644 |
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