Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis

Neogenin, a deleted in colorectal cancer (DCC) family member, has been identified as a receptor for the neuronal axon guidance cues netrins and repulsive guidance molecules repulsive guidance molecules (RGM). RGMc, also called hemojuvelin (HJV), is essential for iron homeostasis. Here we provide evi...

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Autores principales: Lee, Dae-Hoon, Zhou, Li-Juan, Zhou, Zheng, Xie, Jian-Xin, Jung, Ji-Ung, Liu, Yu, Xi, Cai-Xia, Mei, Lin, Xiong, Wen-Cheng
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2010
Materias:
Red Cells, Iron, and Erythropoiesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858467/
https://ncbi.nlm.nih.gov/pubmed/20065295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-11-251199
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