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Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis
Neogenin, a deleted in colorectal cancer (DCC) family member, has been identified as a receptor for the neuronal axon guidance cues netrins and repulsive guidance molecules repulsive guidance molecules (RGM). RGMc, also called hemojuvelin (HJV), is essential for iron homeostasis. Here we provide evi...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858467/ https://ncbi.nlm.nih.gov/pubmed/20065295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-11-251199 |
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