CYR61/CCN1 overexpression in the myeloma microenvironment is associated with superior survival and reduced bone disease

Secreted protein CCN1, encoded by CYR61, is involved in wound healing, angiogenesis, and osteoblast differentiation. We identified CCN1 as a microenvironmental factor produced by mesenchymal cells and overexpressed in bones of a subset of patients with monoclonal gammopathy of undetermined significa...

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Detalhes bibliográficos
Main Authors: Johnson, Sarah K., Stewart, James P., Bam, Rakesh, Qu, Pingping, Barlogie, Bart, van Rhee, Frits, Shaughnessy, John D., Epstein, Joshua, Yaccoby, Shmuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186535/
https://ncbi.nlm.nih.gov/pubmed/25061178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-555813
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