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Role of Bruton’s tyrosine kinase in myeloma cell migration and induction of bone disease
Myeloma cells typically grow in bone, recruit osteoclast precursors and induce their differentiation and activity in areas adjacent to tumor foci. Bruton’s tyrosine kinase (BTK), of the TEC family, is expressed in hematopoietic cells and is particularly involved in B-lymphocyte function and osteocla...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971999/ https://ncbi.nlm.nih.gov/pubmed/23456977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.23433 |
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