Role of Bruton’s tyrosine kinase in myeloma cell migration and induction of bone disease

Myeloma cells typically grow in bone, recruit osteoclast precursors and induce their differentiation and activity in areas adjacent to tumor foci. Bruton’s tyrosine kinase (BTK), of the TEC family, is expressed in hematopoietic cells and is particularly involved in B-lymphocyte function and osteocla...

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Bibliografische gegevens
Hoofdauteurs: Bam, Rakesh, Ling, Wen, Khan, Sharmin, Pennisi, Angela, Venkateshaiah, Sathisha Upparahalli, Li, Xin, van Rhee, Frits, Usmani, Saad, Barlogie, Bart, Shaughnessy, John, Epstein, Joshua, Yaccoby, Shmuel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971999/
https://ncbi.nlm.nih.gov/pubmed/23456977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.23433
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