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Role of Bruton’s tyrosine kinase in myeloma cell migration and induction of bone disease

Myeloma cells typically grow in bone, recruit osteoclast precursors and induce their differentiation and activity in areas adjacent to tumor foci. Bruton’s tyrosine kinase (BTK), of the TEC family, is expressed in hematopoietic cells and is particularly involved in B-lymphocyte function and osteocla...

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Détails bibliographiques
Auteurs principaux: Bam, Rakesh, Ling, Wen, Khan, Sharmin, Pennisi, Angela, Venkateshaiah, Sathisha Upparahalli, Li, Xin, van Rhee, Frits, Usmani, Saad, Barlogie, Bart, Shaughnessy, John, Epstein, Joshua, Yaccoby, Shmuel
Format: Artigo
Langue:Inglês
Publié: 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971999/
https://ncbi.nlm.nih.gov/pubmed/23456977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.23433
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