CYR61/CCN1 overexpression in the myeloma microenvironment is associated with superior survival and reduced bone disease

Secreted protein CCN1, encoded by CYR61, is involved in wound healing, angiogenesis, and osteoblast differentiation. We identified CCN1 as a microenvironmental factor produced by mesenchymal cells and overexpressed in bones of a subset of patients with monoclonal gammopathy of undetermined significa...

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Bibliografiske detaljer
Main Authors: Johnson, Sarah K., Stewart, James P., Bam, Rakesh, Qu, Pingping, Barlogie, Bart, van Rhee, Frits, Shaughnessy, John D., Epstein, Joshua, Yaccoby, Shmuel
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2014
Fag:
Lymphoid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186535/
https://ncbi.nlm.nih.gov/pubmed/25061178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-555813
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