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Homeostatic IL-23 receptor signaling limits Th17 response through IL-22–mediated containment of commensal microbiota
Mammalian hosts are colonized with commensal microbes in various mucosal and epithelial tissues, including the intestinal tract. In mice, the presence of segmented filamentous bacteria (SFB) promotes Th17 differentiation and the development of autoimmune disease. Here, we demonstrate that the IL-23...
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| Hlavní autoři: | , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183330/ https://ncbi.nlm.nih.gov/pubmed/25201978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323852111 |
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