Cargando...
Total Synthesis and Biological Evaluation of Tubulysin U, Tubulysin V, and their Analogs
A stereoselective total synthesis of the cytotoxic natural products tubulysin U, tubulysin V, and its unnatural epimer epi-tubulysin V, is reported. A series of simplified analogs containing N,N-dimethyl-D-alanine as a replacement for the N-terminal N-Me-pipecolinic acid residue of the tubulysins is...
Guardado en:
| Autores principales: | , , , , |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183140/ https://ncbi.nlm.nih.gov/pubmed/19102699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8013579 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|