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Studies toward the Total Synthesis of Itralamide B and Biological Evaluation of Its Structural Analogs
Itralamides A and B were isolated from the lipophilic extract of Lyngbya majuscula collected from the eastern Caribbean. Itralamide B (1) showed cytotoxic activity towards human embryonic kidney cells (HEK293, IC(50) = 6 μM). Preliminary studies disapproved the proposed stereochemistry of itralamide...
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| Publicado no: | Mar Drugs |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4413201/ https://ncbi.nlm.nih.gov/pubmed/25871289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13042085 |
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