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Total Synthesis and Biological Evaluation of Tyroscherin

[Image: see text] The efficient synthesis and biological evaluation of both the reported and revised structures of tyroscherin have been achieved. Central to our synthesis is a cross metathesis reaction that generated the trans-olefin regioselectively. This synthetic strategy enabled the facile mani...

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Autors principals: Tae, Hyun Seop, Hines, John, Schneekloth, Ashley R., Crews, Craig M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175621/
https://ncbi.nlm.nih.gov/pubmed/20831175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol101801u
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