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Neurotrophic peptide aldehydes: Solid phase synthesis of fellutamide B and a simplified analog

A combination of solid phase and solution phase synthetic methods have been used to complete the total synthesis of the neurotrophic lipopeptide aldehyde fellutamide B (2). The β-hydroxy aliphatic tail was prepared by regioselective reductive opening of a cyclic sulfate, and later coupled to a solid...

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Detalhes bibliográficos
Main Authors: Schneekloth, John S., Sanders, John L., Hines, John, Crews, Craig M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2507734/
https://ncbi.nlm.nih.gov/pubmed/16697191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.04.029
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