Hematopoietic but Not Endothelial Cell MyD88 Contributes to Host Defense during Gram-negative Pneumonia Derived Sepsis

Klebsiella pneumoniae is an important cause of sepsis. The common Toll-like receptor adapter myeloid differentiation primary response gene (MyD)88 is crucial for host defense against Klebsiella. Here we investigated the role of MyD88 in myeloid and endothelial cells during Klebsiella pneumosepsis. M...

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Bibliografische gegevens
Hoofdauteurs: van Lieshout, Miriam H. P., Anas, Adam A., Florquin, Sandrine, Hou, Baidong, van't Veer, Cornelis, de Vos, Alex F., van der Poll, Tom
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177915/
https://ncbi.nlm.nih.gov/pubmed/25254554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004368
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