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Hematopoietic but Not Endothelial Cell MyD88 Contributes to Host Defense during Gram-negative Pneumonia Derived Sepsis

Klebsiella pneumoniae is an important cause of sepsis. The common Toll-like receptor adapter myeloid differentiation primary response gene (MyD)88 is crucial for host defense against Klebsiella. Here we investigated the role of MyD88 in myeloid and endothelial cells during Klebsiella pneumosepsis. M...

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Hlavní autoři: van Lieshout, Miriam H. P., Anas, Adam A., Florquin, Sandrine, Hou, Baidong, van't Veer, Cornelis, de Vos, Alex F., van der Poll, Tom
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177915/
https://ncbi.nlm.nih.gov/pubmed/25254554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004368
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