Hematopoietic but Not Endothelial Cell MyD88 Contributes to Host Defense during Gram-negative Pneumonia Derived Sepsis

Klebsiella pneumoniae is an important cause of sepsis. The common Toll-like receptor adapter myeloid differentiation primary response gene (MyD)88 is crucial for host defense against Klebsiella. Here we investigated the role of MyD88 in myeloid and endothelial cells during Klebsiella pneumosepsis. M...

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Bibliografiska uppgifter
Huvudupphovsmän: van Lieshout, Miriam H. P., Anas, Adam A., Florquin, Sandrine, Hou, Baidong, van't Veer, Cornelis, de Vos, Alex F., van der Poll, Tom
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177915/
https://ncbi.nlm.nih.gov/pubmed/25254554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004368
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