Hematopoietic but Not Endothelial Cell MyD88 Contributes to Host Defense during Gram-negative Pneumonia Derived Sepsis

Klebsiella pneumoniae is an important cause of sepsis. The common Toll-like receptor adapter myeloid differentiation primary response gene (MyD)88 is crucial for host defense against Klebsiella. Here we investigated the role of MyD88 in myeloid and endothelial cells during Klebsiella pneumosepsis. M...

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Autors principals: van Lieshout, Miriam H. P., Anas, Adam A., Florquin, Sandrine, Hou, Baidong, van't Veer, Cornelis, de Vos, Alex F., van der Poll, Tom
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177915/
https://ncbi.nlm.nih.gov/pubmed/25254554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004368
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