The Polysaccharide Capsule of Streptococcus pneumonia Partially Impedes MyD88-Mediated Immunity during Pneumonia in Mice

Toll-like receptors (TLR) and the downstream adaptor protein MyD88 are considered crucial for protective immunity during bacterial infections. Streptococcus (S.) pneumoniae is a human respiratory pathogen and a large majority of clinical pneumococcal isolates expresses an external polysaccharide cap...

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Pubblicato in:PLoS One
Autori principali: de Vos, Alex F., Dessing, Mark C., Lammers, Adriana J. J., de Porto, Alexander P. N. A., Florquin, Sandrine, de Boer, Onno J., de Beer, Regina, Terpstra, Sanne, Bootsma, Hester J., Hermans, Peter W., van ‘t Veer, Cornelis, van der Poll, Tom
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336322/
https://ncbi.nlm.nih.gov/pubmed/25700108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118181
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