The Polysaccharide Capsule of Streptococcus pneumonia Partially Impedes MyD88-Mediated Immunity during Pneumonia in Mice

Toll-like receptors (TLR) and the downstream adaptor protein MyD88 are considered crucial for protective immunity during bacterial infections. Streptococcus (S.) pneumoniae is a human respiratory pathogen and a large majority of clinical pneumococcal isolates expresses an external polysaccharide cap...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: de Vos, Alex F., Dessing, Mark C., Lammers, Adriana J. J., de Porto, Alexander P. N. A., Florquin, Sandrine, de Boer, Onno J., de Beer, Regina, Terpstra, Sanne, Bootsma, Hester J., Hermans, Peter W., van ‘t Veer, Cornelis, van der Poll, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336322/
https://ncbi.nlm.nih.gov/pubmed/25700108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118181
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