Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia

Streptococcus (S.) pneumoniae is the most common causative pathogen in community-acquired pneumonia. Nucleotide-binding oligomerization domain-containing (NOD) 2 is a pattern recognition receptor located in the cytosol of myeloid cells that is able to detect peptidoglycan fragments of S. pneumoniae....

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Pubblicato in:PLoS One
Autori principali: Hommes, Tijmen J., van Lieshout, Miriam H., van ‘t Veer, Cornelis, Florquin, Sandrine, Bootsma, Hester J., Hermans, Peter W., de Vos, Alex F., van der Poll, Tom
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682639/
https://ncbi.nlm.nih.gov/pubmed/26673231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145138
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