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Single Immunoglobulin Interleukin-1 Receptor-Related Molecule Impairs Host Defense during Pneumonia and Sepsis Caused by Streptococcus Pneumoniae

Streptococcus pneumoniae is a common cause of pneumonia and sepsis. Toll-like receptors (TLRs) play a pivotal role in the host defense against infection. In this study, we sought to determine the role of single immunoglobulin interleukin-1 receptor-related molecule (SIGIRR a.k.a. TIR8), a negative r...

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書目詳細資料
發表在:J Innate Immun
Main Authors: Blok, Dana C., van Lieshout, Miriam H.P., Hoogendijk, Arie J., Florquin, Sandrine, de Boer, Onno J., Garlanda, Cecilia, Mantovani, Alberto, van't Veer, Cornelis, de Vos, Alex F., van der Poll, Tom
格式: Artigo
語言:Inglês
出版: S. Karger AG 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741518/
https://ncbi.nlm.nih.gov/pubmed/24556793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000358239
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