Interleukin-1 Receptor–Associated Kinase M–Deficient Mice Demonstrate an Improved Host Defense during Gram-negative Pneumonia

Pneumonia is a common cause of morbidity and mortality and the most frequent source of sepsis. Bacteria that try to invade normally sterile body sites are recognized by innate immune cells through pattern recognition receptors, among which toll-like receptors (TLRs) feature prominently. Interleukin-...

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Main Authors: Hoogerwerf, Jacobien J, van der Windt, Gerritje JW, Blok, Dana C, Hoogendijk, Arie J, de Vos, Alex F, van ‘t Veer, Cornelis, Florquin, Sandrine, Kobayashi, Koichi S, Flavell, Richard A, van der Poll, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475335/
https://ncbi.nlm.nih.gov/pubmed/22729155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00450
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