CD44 Deficiency Is Associated with Increased Bacterial Clearance but Enhanced Lung Inflammation During Gram-Negative Pneumonia

Klebsiella pneumoniae is a frequently isolated causative pathogen in respiratory tract infections. CD44 is a transmembrane adhesion molecule that has been implicated in several immunological processes. To determine the role of CD44 during Klebsiella pneumonia, we intranasally infected wild-type and...

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Главные авторы: van der Windt, Gerritje J.W., Florquin, Sandrine, de Vos, Alex F., van't Veer, Cornelis, Queiroz, Karla C.S., Liang, Jiurong, Jiang, Dianhua, Noble, Paul W., van der Poll, Tom
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2010
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Regular Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966805/
https://ncbi.nlm.nih.gov/pubmed/20864681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100562
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