Streptococcus pneumoniae Serine Protease HtrA, but Not SFP or PrtA, Is a Major Virulence Factor in Pneumonia

Streptococcus (S.) pneumoniae is a common causative pathogen in pneumonia. Serine protease orthologs expressed by a variety of bacteria have been found of importance for virulence. Previous studies have identified two serine proteases in S. pneumoniae, HtrA (high-temperature requirement A) and PrtA...

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Main Authors: de Stoppelaar, Sacha F., Bootsma, Hester J., Zomer, Aldert, Roelofs, Joris J. T. H., Hermans, Peter W. M., van ’t Veer, Cornelis, van der Poll, Tom
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823867/
https://ncbi.nlm.nih.gov/pubmed/24244609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080062
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