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Role of HtrA in the Virulence and Competence of Streptococcus pneumoniae

HtrA is a major virulence factor of Streptococcus pneumoniae (the pneumococcus). Deletion of the gene for HtrA from strain D39 of the pneumococcus completely abolished its virulence in mouse models of pneumonia and bacteremia, while the virulence of a second strain (TIGR4) was dramatically reduced....

詳細記述

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書誌詳細
主要な著者: Ibrahim, Yasser Musa, Kerr, Alison R., McCluskey, Jackie, Mitchell, Tim J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC415679/
https://ncbi.nlm.nih.gov/pubmed/15155668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.6.3584-3591.2004
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