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Thrombocytopenia impairs host defense in gram-negative pneumonia–derived sepsis in mice
Thrombocytopenia is a common finding in sepsis and associated with a worse outcome. We used a mouse model of pneumonia-derived sepsis caused by the human pathogen Klebsiella pneumoniae to study the role of platelets in host response to sepsis. Platelet counts (PCs) were reduced to less than a median...
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| Publicado no: | Blood |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4263985/ https://ncbi.nlm.nih.gov/pubmed/25301709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-05-573915 |
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