Dopamine Signaling Leads to Loss of Polycomb Repression and Aberrant Gene Activation in Experimental Parkinsonism

Polycomb group (PcG) proteins bind to and repress genes in embryonic stem cells through lineage commitment to the terminal differentiated state. PcG repressed genes are commonly characterized by the presence of the epigenetic histone mark H3K27me3, catalyzed by the Polycomb repressive complex 2. Her...

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Detalhes bibliográficos
Main Authors: Södersten, Erik, Feyder, Michael, Lerdrup, Mads, Gomes, Ana-Luisa, Kryh, Hanna, Spigolon, Giada, Caboche, Jocelyne, Fisone, Gilberto, Hansen, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177666/
https://ncbi.nlm.nih.gov/pubmed/25254549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004574
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