A role for mitogen- and stress-activated kinase 1 in L-DOPA-induced dyskinesia and ΔFosB expression

BACKGROUND: Abnormal regulation of extracellular signal-regulated kinases 1 and 2 (ERK) has been implicated in L-DOPA-induced dyskinesia (LID), a motor complication affecting Parkinson’s disease (PD) patients subjected to standard pharmacotherapy. We examined the involvement in LID of the mitogen- a...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Feyder, Michael, Södersten, Erik, Santini, Emanuela, Vialou, Vincent, LaPlant, Quincey C., Watts, Emily L., Spigolon, Giada, Hansen, Klaus, Caboche, Jocelyne, Nestler, Eric, Fisone, Gilberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309747/
https://ncbi.nlm.nih.gov/pubmed/25193242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.07.019
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