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Functional Role of the N-Terminal Domain of ΔFosB in Response to Stress and Drugs of Abuse

Previous work has implicated the transcription factor, ΔFosB, acting in the nucleus accumbens, in mediating the pro-rewarding effects of drugs of abuse such as cocaine as well as in mediating resilience to chronic social stress. However, the transgenic and viral gene transfer models used to establis...

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Publicado en:Neuroscience
Autores principales: Ohnishi, Yoshinori N., Ohnishi, Yoko H., Vialou, Vincent, Mouzon, Ezekiell, LaPlant, Quincey, Nishi, Akinori, Nestler, Eric J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268105/
https://ncbi.nlm.nih.gov/pubmed/25313003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.10.002
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