ΔFosB in brain reward circuits mediates resilience to stress and antidepressant responses

In contrast to the vast literature on stress effects on the brain, relatively little is known about the molecular mechanisms of resilience, the ability of some individuals to escape the deleterious effects of stress. Here we show that the transcription factor, ΔFosB, mediates an essential mechanism...

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Detalhes bibliográficos
Main Authors: Vialou, Vincent, Robison, Alfred J., LaPlant, Quincey C., Covington, Herb E., Dietz, David M., Ohnishi, Yoshinori N., Mouzon, Ezekiell, Rush, Augustus J., Watts, Emily L., Wallace, Deanna L., Iniguez, Sergio D., Ohnishi, Yoko H., Steiner, Michel A., Warren, Brandon, Krishnan, Vaishnav, Neve, Rachael L., Ghose, Subroto, Berton, Olivier, Tamminga, Carol A., Nestler, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895556/
https://ncbi.nlm.nih.gov/pubmed/20473292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2551
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