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ΔFosB Induction in Prefrontal Cortex by Antipsychotic Drugs is Associated with Negative Behavioral Outcomes

ΔFosB, a FosB gene product, is induced in the prefrontal cortex (PFC) by repeated exposure to several stimuli including antipsychotic drugs such as haloperidol. However, the functional consequences of increased ΔFosB expression following antipsychotic treatment have not been explored. Here, we asses...

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Main Authors: Dietz, David M, Kennedy, Pamela J, Sun, HaoSheng, Maze, Ian, Gancarz, Amy M, Vialou, Vincent, Koo, Ja Wook, Mouzon, Ezekiell, Ghose, Subroto, Tamminga, Carol A, Nestler, Eric J
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895248/
https://ncbi.nlm.nih.gov/pubmed/24067299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.255
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