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ΔFosB Induction in Prefrontal Cortex by Antipsychotic Drugs is Associated with Negative Behavioral Outcomes

ΔFosB, a FosB gene product, is induced in the prefrontal cortex (PFC) by repeated exposure to several stimuli including antipsychotic drugs such as haloperidol. However, the functional consequences of increased ΔFosB expression following antipsychotic treatment have not been explored. Here, we asses...

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Detalhes bibliográficos
Main Authors: Dietz, David M, Kennedy, Pamela J, Sun, HaoSheng, Maze, Ian, Gancarz, Amy M, Vialou, Vincent, Koo, Ja Wook, Mouzon, Ezekiell, Ghose, Subroto, Tamminga, Carol A, Nestler, Eric J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895248/
https://ncbi.nlm.nih.gov/pubmed/24067299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.255
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