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Signal transduction in l-DOPA-induced dyskinesia: from receptor sensitization to abnormal gene expression

A large number of signaling abnormalities have been implicated in the emergence and expression of l-DOPA-induced dyskinesia (LID). The primary cause for many of these changes is the development of sensitization at dopamine receptors located on striatal projection neurons (SPN). This initial priming,...

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Veröffentlicht in:J Neural Transm (Vienna)
Hauptverfasser: Spigolon, Giada, Fisone, Gilberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Vienna 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060907/
https://ncbi.nlm.nih.gov/pubmed/29396608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00702-018-1847-7
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