Critical Involvement of cAMP/DARPP-32 and Extracellular Signal-Regulated Protein Kinase Signaling in l-DOPA-Induced Dyskinesia

The molecular basis of l-3,4-dihydroxyphenylalanine (l-DOPA)-induced dyskinesia (LID), one of the major hindrances in the current therapy for Parkinson's disease, is still unclear. We show that attenuation of cAMP signaling in the medium spiny neurons of the striatum, achieved by genetic inacti...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Santini, Emanuela, Valjent, Emmanuel, Usiello, Alessandro, Carta, Manolo, Borgkvist, Anders, Girault, Jean-Antoine, Hervé, Denis, Greengard, Paul, Fisone, Gilberto
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672217/
https://ncbi.nlm.nih.gov/pubmed/17596448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0852-07.2007
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados