Dysregulated mTORC1-Dependent Translational Control: From Brain Disorders to Psychoactive Drugs

Por Santini, Emanuela, Klann, Eric
Publicado em 2011

Reciprocal Signaling Between Translational Control Pathways and Synaptic Proteins in Autism Spectrum Disorders

Por Santini, Emanuela, Klann, Eric
Publicado no Sci Signal (2014)

Requirement of Mammalian Target of Rapamycin Complex 1 Downstream Effectors in Cued Fear Memory Reconsolidation and Its Persistence

Por Huynh, Thu N., Santini, Emanuela, Klann, Eric
Publicado em 2014

Mechanisms of Translation Control Underlying Long-lasting Synaptic Plasticity and the Consolidation of Long-term Memory

Por Santini, Emanuela, Huynh, Thu N., Klann, Eric
Publicado no Prog Mol Biol Transl Sci (2014)

Impaired Social Interactions and Motor Learning Skills in Tuberous Sclerosis Complex Model Mice Expressing a Dominant/Negative Form of Tuberin

Por Chévere-Torres, Itzamarie, Maki, Jordan M., Santini, Emanuela, Klann, Eric
Publicado em 2011

Dopamine- and cAMP-regulated Phosphoprotein of 32-kDa (DARPP-32)-dependent Activation of Extracellular Signal-regulated Kinase (ERK) and Mammalian Target of Rapamycin Complex 1 (mT...

Por Santini, Emanuela, Feyder, Michael, Gangarossa, Giuseppe, Bateup, Helen S., Greengard, Paul, Fisone, Gilberto
Publicado em 2012

Gα(olf) Mutation Allows Parsing the Role of cAMP-Dependent and Extracellular Signal-Regulated Kinase-Dependent Signaling in l-3,4-Dihydroxyphenylalanine-Induced Dyskinesia

Por Alcacer, Cristina, Santini, Emanuela, Valjent, Emmanuel, Gaven, Florence, Girault, Jean-Antoine, Hervé, Denis
Publicado no J Neurosci (2012)

eIF4E/Fmr1 Double Mutant Mice Display Cognitive Impairment in Addition to ASD-like Behaviors

Por Huynh, Thu N., Shah, Manan, Koo, So Yeon, Faraud, Kirsten S., Santini, Emanuela, Klann, Eric
Publicado no Neurobiol Dis (2015)

Distinct Changes in cAMP and Extracellular Signal-Regulated Protein Kinase Signalling in L-DOPA-Induced Dyskinesia

Por Santini, Emanuela, Sgambato-Faure, Veronique, Li, Qin, Savasta, Marc, Dovero, Sandra, Fisone, Gilberto, Bezard, Erwan
Publicado em 2010

Mitochondrial Superoxide Contributes to Hippocampal Synaptic Dysfunction and Memory Deficits in Angelman Syndrome Model Mice

Por Santini, Emanuela, Turner, Kathryn L., Ramaraj, Akila B., Murphy, Michael P., Klann, Eric, Kaphzan, Hanoch
Publicado no J Neurosci (2015)

Current Perspectives in Autism Spectrum Disorder: From Genes to Therapy

Por Chahrour, Maria, O'Roak, Brian J., Santini, Emanuela, Samaco, Rodney C., Kleiman, Robin J., Manzini, M. Chiara
Publicado no J Neurosci (2016)

Genetic Reduction of the α1 Subunit of Na/K-ATPase Corrects Multiple Hippocampal Phenotypes in Angelman Syndrome

Por Kaphzan, Hanoch, Buffington, Shelly A., Ramaraj, Akila B., Lingrel, Jerry B., Rasband, Matthew N., Santini, Emanuela, Klann, Eric
Publicado em 2013

Reducing eIF4E-eIF4G Interactions Restores the Balance Between Protein Synthesis and Actin Dynamics in Fragile X Syndrome Model Mice()

Por Santini, Emanuela, Huynh, Thu N., Longo, Francesco, Koo, So Yeon, Mojica, Edward, D’Andrea, Laura, Bagni, Claudia, Klann, Eric
Publicado no Sci Signal (2017)

Critical Involvement of cAMP/DARPP-32 and Extracellular Signal-Regulated Protein Kinase Signaling in l-DOPA-Induced Dyskinesia

Por Santini, Emanuela, Valjent, Emmanuel, Usiello, Alessandro, Carta, Manolo, Borgkvist, Anders, Girault, Jean-Antoine, Hervé, Denis, Greengard, Paul, Fisone, Gilberto
Publicado no J Neurosci (2007)

Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors

Por Bateup, Helen S., Santini, Emanuela, Shen, Weixing, Birnbaum, Shari, Valjent, Emmanuel, Surmeier, D. James, Fisone, Gilberto, Nestler, Eric J., Greengard, Paul
Publicado em 2010

Exaggerated Translation Causes Synaptic and Behavioral Aberrations Associated with Autism

Por Santini, Emanuela, Huynh, Thu N., MacAskill, Andrew F., Carter, Adam G., Ruggero, Davide, Pierre, Philippe, Kaphzan, Hanoch, Klann, Eric
Publicado em 2012

Multiple components of eIF4F are required for protein synthesis-dependent hippocampal long-term potentiation

Por Hoeffer, Charles A., Santini, Emanuela, Ma, Tao, Arnold, Elizabeth C., Whelan, Ashley M., Wong, Helen, Pierre, Philippe, Pelletier, Jerry, Klann, Eric
Publicado em 2013

Metabotropic Glutamate Receptor-dependent Long-term Depression is Impaired Due to Elevated ERK Signaling in the ΔRG Mouse Model of Tuberous Sclerosis Complex

Por Chévere-Torres, Itzamarie, Kaphzan, Hanoch, Bhattacharya, Aditi, Kang, Areum, Maki, Jordan M., Gambello, Michael J., Arbiser, Jack L., Santini, Emanuela, Klann, Eric
Publicado em 2011

mTOR Suppresses Macroautophagy During Striatal Postnatal Development and Is Hyperactive in Mouse Models of Autism Spectrum Disorders

Por Lieberman, Ori J., Cartocci, Veronica, Pigulevskiy, Irena, Molinari, Maya, Carbonell, Josep, Broseta, Miguel Bellés, Post, Michael R., Sulzer, David, Borgkvist, Anders, Santini, Emanuela
Publicado no Front Cell Neurosci (2020)

Axon TRAP reveals learning-associated alterations in cortical axonal mRNAs in the lateral amygdala

Por Ostroff, Linnaea E, Santini, Emanuela, Sears, Robert, Deane, Zachary, Kanadia, Rahul N, LeDoux, Joseph E, Lhakhang, Tenzin, Tsirigos, Aristotelis, Heguy, Adriana, Klann, Eric
Publicado no eLife (2019)