mTOR Suppresses Macroautophagy During Striatal Postnatal Development and Is Hyperactive in Mouse Models of Autism Spectrum Disorders

Macroautophagy (hereafter referred to as autophagy) plays a critical role in neuronal function related to development and degeneration. Here, we investigated whether autophagy is developmentally regulated in the striatum, a brain region implicated in neurodevelopmental disease. We demonstrate that a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Cell Neurosci
Egile Nagusiak: Lieberman, Ori J., Cartocci, Veronica, Pigulevskiy, Irena, Molinari, Maya, Carbonell, Josep, Broseta, Miguel Bellés, Post, Michael R., Sulzer, David, Borgkvist, Anders, Santini, Emanuela
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2020
Gaiak:
Neuroscience
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136750/
https://ncbi.nlm.nih.gov/pubmed/32296308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00070
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak