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Synaptic plasticity may underlie L-DOPA induced dyskinesia

L-DOPA provides highly effective treatment for Parkinson’s disease, but L-DOPA induced dyskinesia (LID) is a very debilitating response that eventually is presented by a majority of patients. A central issue in understanding the basis of LID is whether it is due to a response to chronic L-DOPA over...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Opin Neurobiol
Hauptverfasser: Borgkvist, Anders, Lieberman, Ori J, Sulzer, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825254/
https://ncbi.nlm.nih.gov/pubmed/29125979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conb.2017.10.021
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