Mitochondrial Superoxide Contributes to Hippocampal Synaptic Dysfunction and Memory Deficits in Angelman Syndrome Model Mice

Angelman syndrome (AS) is a neurodevelopmental disorder associated with developmental delay, lack of speech, motor dysfunction, and epilepsy. In the majority of the patients, AS is caused by the deletion of small portions of maternal chromosome 15 harboring the UBE3A gene. This results in a lack of...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Santini, Emanuela, Turner, Kathryn L., Ramaraj, Akila B., Murphy, Michael P., Klann, Eric, Kaphzan, Hanoch
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682786/
https://ncbi.nlm.nih.gov/pubmed/26658871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2246-15.2015
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