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Mitochondrial Superoxide Contributes to Hippocampal Synaptic Dysfunction and Memory Deficits in Angelman Syndrome Model Mice

Angelman syndrome (AS) is a neurodevelopmental disorder associated with developmental delay, lack of speech, motor dysfunction, and epilepsy. In the majority of the patients, AS is caused by the deletion of small portions of maternal chromosome 15 harboring the UBE3A gene. This results in a lack of...

詳細記述

保存先:
書誌詳細
出版年:J Neurosci
主要な著者: Santini, Emanuela, Turner, Kathryn L., Ramaraj, Akila B., Murphy, Michael P., Klann, Eric, Kaphzan, Hanoch
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682786/
https://ncbi.nlm.nih.gov/pubmed/26658871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2246-15.2015
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