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Mitochondrial Superoxide Contributes to Hippocampal Synaptic Dysfunction and Memory Deficits in Angelman Syndrome Model Mice

Angelman syndrome (AS) is a neurodevelopmental disorder associated with developmental delay, lack of speech, motor dysfunction, and epilepsy. In the majority of the patients, AS is caused by the deletion of small portions of maternal chromosome 15 harboring the UBE3A gene. This results in a lack of...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Santini, Emanuela, Turner, Kathryn L., Ramaraj, Akila B., Murphy, Michael P., Klann, Eric, Kaphzan, Hanoch
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682786/
https://ncbi.nlm.nih.gov/pubmed/26658871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2246-15.2015
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