REST–Mediated Recruitment of Polycomb Repressor Complexes in Mammalian Cells

Polycomb Repressive Complex (PRC) 1 and PRC2 regulate genes involved in differentiation and development. However, the mechanism for how PRC1 and PRC2 are recruited to genes in mammalian cells is unclear. Here we present evidence for an interaction between the transcription factor REST, PRC1, and PRC...

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Autori principali: Dietrich, Nikolaj, Lerdrup, Mads, Landt, Eskild, Agrawal-Singh, Shuchi, Bak, Mads, Tommerup, Niels, Rappsilber, Juri, Södersten, Erik, Hansen, Klaus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291536/
https://ncbi.nlm.nih.gov/pubmed/22396653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002494
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