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Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus

The Polycomb group (PcG) proteins are essential for embryogenesis, and their expression is often found deregulated in human cancer. The PcGs form two major protein complexes, called polycomb repressive complexes 1 and 2 (PRC1 and PRC2) whose function is to maintain transcriptional repression. Here,...

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Detalhes bibliográficos
Main Authors: Dietrich, Nikolaj, Bracken, Adrian P, Trinh, Emmanuelle, Schjerling, Charlotte K, Koseki, Haruhiko, Rappsilber, Juri, Helin, Kristian, Hansen, Klaus H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829390/
https://ncbi.nlm.nih.gov/pubmed/17332741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601632
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