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Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

The Polycomb group (PcG) proteins form chromatin-modifying complexes that are essential for embryonic development and stem cell renewal and are commonly deregulated in cancer. Here, we identify their target genes using genome-wide location analysis in human embryonic fibroblasts. We find that Polyco...

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Detalhes bibliográficos
Main Authors: Bracken, Adrian P., Dietrich, Nikolaj, Pasini, Diego, Hansen, Klaus H., Helin, Kristian
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472472/
https://ncbi.nlm.nih.gov/pubmed/16618801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.381706
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