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Polycomb complexes act redundantly to repress genomic repeats and genes

Polycomb complexes establish chromatin modifications for maintaining gene repression and are essential for embryonic development in mice. Here we use pluripotent embryonic stem (ES) cells to demonstrate an unexpected redundancy between Polycomb-repressive complex 1 (PRC1) and PRC2 during the formati...

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Hlavní autoři: Leeb, Martin, Pasini, Diego, Novatchkova, Maria, Jaritz, Markus, Helin, Kristian, Wutz, Anton
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811828/
https://ncbi.nlm.nih.gov/pubmed/20123906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.544410
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