Polycomb complexes act redundantly to repress genomic repeats and genes

Polycomb complexes establish chromatin modifications for maintaining gene repression and are essential for embryonic development in mice. Here we use pluripotent embryonic stem (ES) cells to demonstrate an unexpected redundancy between Polycomb-repressive complex 1 (PRC1) and PRC2 during the formati...

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Autors principals: Leeb, Martin, Pasini, Diego, Novatchkova, Maria, Jaritz, Markus, Helin, Kristian, Wutz, Anton
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2010
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811828/
https://ncbi.nlm.nih.gov/pubmed/20123906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.544410
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