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The Polycomb Repressive Complex 2 Is a Potential Target of SUMO Modifications

BACKGROUND: The Polycomb Repressive Complex 2 (PRC2) functions as a transcriptional repressor through a mechanism that involves methylation of Histone H3 at lysine 27. The PRC2 complex activity is essential for cellular proliferation, development, and cell fate decisions. PRC2 target genes include i...

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Bibliografski detalji
Glavni autori: Riising, Eva Madi, Boggio, Roberto, Chiocca, Susanna, Helin, Kristian, Pasini, Diego
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442188/
https://ncbi.nlm.nih.gov/pubmed/18628979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002704
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