REST–Mediated Recruitment of Polycomb Repressor Complexes in Mammalian Cells

Polycomb Repressive Complex (PRC) 1 and PRC2 regulate genes involved in differentiation and development. However, the mechanism for how PRC1 and PRC2 are recruited to genes in mammalian cells is unclear. Here we present evidence for an interaction between the transcription factor REST, PRC1, and PRC...

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Detalhes bibliográficos
Main Authors: Dietrich, Nikolaj, Lerdrup, Mads, Landt, Eskild, Agrawal-Singh, Shuchi, Bak, Mads, Tommerup, Niels, Rappsilber, Juri, Södersten, Erik, Hansen, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291536/
https://ncbi.nlm.nih.gov/pubmed/22396653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002494
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