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Multiple LacI-mediated loops revealed by Bayesian statistics and tethered particle motion

The bacterial transcription factor LacI loops DNA by binding to two separate locations on the DNA simultaneously. Despite being one of the best-studied model systems for transcriptional regulation, the number and conformations of loop structures accessible to LacI remain unclear, though the importan...

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Detalhes bibliográficos
Main Authors: Johnson, Stephanie, van de Meent, Jan-Willem, Phillips, Rob, Wiggins, Chris H., Lindén, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176382/
https://ncbi.nlm.nih.gov/pubmed/25120267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku563
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