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First-principles calculation of DNA looping in tethered particle experiments
We calculate the probability of DNA loop formation mediated by regulatory proteins such as Lac repressor (LacI), using a mathematical model of DNA elasticity. Our model is adapted to calculating quantities directly observable in tethered particle motion (TPM) experiments, and it accounts for all the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3298194/ https://ncbi.nlm.nih.gov/pubmed/19571369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/6/2/025001 |
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