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Lac repressor hinge flexibility and DNA looping: single molecule kinetics by tethered particle motion
The tethered particle motion (TPM) allows the direct detection of activity of a variety of biomolecules at the single molecule level. First pioneered for RNA polymerase, it has recently been applied also to other enzymes. In this work we employ TPM for a systematic investigation of the kinetics of D...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1524907/ https://ncbi.nlm.nih.gov/pubmed/16835309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl393 |
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