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Single-molecule manipulation reveals supercoiling-dependent modulation of lac repressor-mediated DNA looping
Gene expression regulation is a fundamental biological process which deploys specific sets of genomic information depending on physiological or environmental conditions. Several transcription factors (including lac repressor, LacI) are present in the cell at very low copy number and increase their l...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2377426/ https://ncbi.nlm.nih.gov/pubmed/18310101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn071 |
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