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Single-molecule manipulation reveals supercoiling-dependent modulation of lac repressor-mediated DNA looping

Gene expression regulation is a fundamental biological process which deploys specific sets of genomic information depending on physiological or environmental conditions. Several transcription factors (including lac repressor, LacI) are present in the cell at very low copy number and increase their l...

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Bibliografske podrobnosti
Main Authors: Normanno, Davide, Vanzi, Francesco, Pavone, Francesco Saverio
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377426/
https://ncbi.nlm.nih.gov/pubmed/18310101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn071
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