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Single-Molecule Spectroscopic Determination of Lac Repressor-DNA Loop Conformation
The Escherichia coli lactose repressor protein (LacI) provides a classic model for understanding protein-induced DNA looping. LacI has a C-terminal four-helix bundle tetramerization domain that may act as a flexible hinge. In previous work, several DNA constructs, each containing two lac operators b...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Biophysical Society
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366758/ https://ncbi.nlm.nih.gov/pubmed/16085773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.067728 |
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