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Fluorescence Resonance Energy Transfer over ∼130 Basepairs in Hyperstable Lac Repressor-DNA Loops

Lac repressor (LacI) binds two operator DNA sites, looping the intervening DNA. DNA molecules containing two lac operators bracketing a sequence-directed bend were previously shown to form hyperstable LacI-looped complexes. Biochemical studies suggested that orienting the operators outward relative...

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Auteurs principaux: Edelman, Laurence M., Cheong, Raymond, Kahn, Jason D.
Format: Artigo
Langue:Inglês
Publié: Biophysical Society 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302690/
https://ncbi.nlm.nih.gov/pubmed/12547794
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