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Computational Analysis of Looping of a Large Family of Highly Bent DNA by LacI
Sequence-dependent intrinsic curvature of DNA influences looping by regulatory proteins such as LacI and NtrC. Curvature can enhance stability and control shape, as observed in LacI loops formed with three designed sequences with operators bracketing an A-tract bend. We explore geometric, topologica...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2599832/ https://ncbi.nlm.nih.gov/pubmed/18931251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.142471 |
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