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Computational Analysis of Looping of a Large Family of Highly Bent DNA by LacI
Sequence-dependent intrinsic curvature of DNA influences looping by regulatory proteins such as LacI and NtrC. Curvature can enhance stability and control shape, as observed in LacI loops formed with three designed sequences with operators bracketing an A-tract bend. We explore geometric, topologica...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2599832/ https://ncbi.nlm.nih.gov/pubmed/18931251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.142471 |
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