Intrinsic Curvature of DNA Influences LacR-Mediated Looping

Protein-mediated DNA looping is a common mechanism for regulating gene expression. Loops occur when a protein binds to two operators on the same DNA molecule. The probability of looping is controlled, in part, by the basepair sequence of inter-operator DNA, which influences its structural properties...

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Autors principals: Goyal, Sachin, Lillian, Todd, Blumberg, Seth, Meiners, Jens-Christian, Meyhöfer, Edgar, Perkins, N. C.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2007
Matèries:
Nucleic Acids
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2098735/
https://ncbi.nlm.nih.gov/pubmed/17766355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.112268
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